Pharmacogenomics, pharmacokinetics and pharmacodynamics: interaction with biological differences between men and women

F Franconi, I Campesi - British journal of pharmacology, 2014 - Wiley Online Library
… Nevertheless, the recruitment of women for clinical … , pharmacokinetic differences between
males and females are more numerous and consistent than disparities in pharmacodynamics. …

Biologic and molecular mechanisms for sex differences in pharmacokinetics, pharmacodynamics and pharmacogenetics: Part II

M Anthony, MJ Berg - Journal of women's health & gender-based …, 2002 - liebertpub.com
… , other biological differences between women and men are weight, … of issues relevant to
women during drug development, … kinetics and the pharmacokinetic interactions between drugs …

Biologic and molecular mechanisms for sex differences in pharmacokinetics, pharmacodynamics, and pharmacogenetics: Part I

M Anthony, MJ Berg - Journal of women's health & gender-based …, 2002 - liebertpub.com
… There are pharmacological differences between women and men that have … of biological
sex on drug interactions. In other drug interaction studies that included both men and women, …

Sex differences in pharmacokinetics and pharmacodynamics

M Gandhi, F Aweeka, RM Greenblatt… - Annu. Rev. Pharmacol …, 2004 - annualreviews.org
… theorized to stem from variations between men and women in factors such as … the biologic
basis of differences in pharmacokinetics and … Although pharmacogenomic studies reveal that …

Sex differences in pharmacokinetics and pharmacodynamics

OP Soldin, DR Mattison - Clinical pharmacokinetics, 2009 - Springer
differences as biologically based differences in men and … that sex differences between men
and women result in similar … drug interactions are due to alterations in pharmacokinetics — in …

principles of pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and clinical implications

YWF Lam - Pharmacogenomics, 2019 - Elsevier
… attributed to innate differences among individuals in their … Despite the scientific advances
made, personalized medicine … could affect the potential for drug interaction with paroxetine, a …

En route to precision medicine through the integration of biological sex into pharmacogenomics

L Gaignebet, G Kararigas - Clinical Science, 2017 - portlandpress.com
… We conclude that the interaction of sex with genetic … assessment of pharmacokinetics
and pharmacodynamics, or the … The biological differences between men and women may …

How important are gender differences in pharmacokinetics?

B Meibohm, I Beierle, H Derendorf - Clinical pharmacokinetics, 2002 - Springer
… in women might be classified as drug-drug interactions,[5,12,… the paper to ‘gender differences
according to the common … discussed biological differences between men and women are …

Sex-related differences in pharmacokinetics and pharmacodynamics of frequently prescribed drugs: a review of the literature

A Farkouh, T Riedl, R Gottardi, M Czejka… - Advances in …, 2020 - Springer
… in men and women [4]. Importantly, there are also significant differences between men and
women in … In contrast, women benefit more from opioids that interact with the κ-receptor, eg …

Gender differences in drug responses

F Franconi, S Brunelleschi, L Steardo… - Pharmacological research, 2007 - Elsevier
… Since sex is a fundamental biological variable that cannot be … and pharmacogenetics.
Moreover, this article gives a quick … Traditional risk factors differ between men and women. …